fNIRS is potentially the only imaging method that may be capable to measure both hemodynamics and neuronal activity. The Event-Related Optical Signal, caused by changes in light scattering from activated neurons, is observable when employing high frequency sampling with fNIRS.
X.-S. Hu, K.-S. Hong, and S. S. Ge, “Recognition of stimulus-evoked neuronal optical response by identifying chaos levels of near-infrared spectroscopy time series,” Neurosci. Lett., vol. 504, no. 2, pp. 115–120, Oct. 2011.
A. V. Medvedev, J. Kainerstorfer, S. V. Borisov, R. L. Barbour, and J. VanMeter, “Event-related fast optical signal in a rapid object recognition task: improving detection by the independent component analysis,” Brain Res., vol. 1236, pp. 145–158, Oct. 2008.
For an informative discussion on the various strategies of optical imaging techniques, please visit:
http://www.nibib.nih.gov/science-education/science-topics/optical-imaging;
http://www.report.nih.gov/nihfactsheets/ViewFactSheet.aspx?csid=105.
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